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KMID : 0371420160910010051
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Annals of Surgical Treatment and Research
2016 Volume.91 No. 1 p.51 ~ p.55
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Difficult diagnosis and localization of focal nesidioblastosis: clinical implications of 68Gallium-DOTA-D-Phe1-Tyr3-octreotide PET scanning
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Kim Jae-Ri
Jang Jin-Young
Shin Yong-Chan
Cho Young-Min
Kim Hong-Beom
Kwon Woo-Il
Han Young-Min
Kim Sun-Whe
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Abstract
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Focal nesidioblastosis is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. Because it is difficult to localize and detect with current imaging modalities, nesidioblastosis is challenging for biliary-pancreatic surgeons. 68Gallium-DOTA-D-Phe1-Tyr3-octreotide PET scanning and 111indium-pentetreotide diethylene triamine pentaacetic acid octreotide scanning may be superior to conventional imaging modalities in determining the localization of nesidioblastosis. We report the successful surgical treatment of a 54-year-old woman with focal hyperplasia of the islets of Langerhans, who experienced frequent hypoglycemic symptoms and underwent various diagnostic examinations with different results.
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KEYWORD
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Nesidioblastosis, Ga(III)-DOTATOC, Positron-emission tomography
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